SciAnalytical has established collaborations with early stage biotechnology companies as well as publicly traded pharmaceutical companies. Projects span medicinal chemistry services (LC/UV/ELSD/MS), absorption screening and flux analysis by LC/MS/MS, mechanism of action studies, biomarker/target engagement confirmation, ADMET, bioanalysis (drug exposure), PK-PD as well as special projects.
State-of-art high resolution HPLC/UV/ELSD/MS analysis to support medicinal chemistry projects, including reaction monitoring, final product purity assessment, formulation analysis.
Turn-around times are industry-leading. You can expect results within 24 hours of sample submission.
High performance LC/MS/MS analysis to support plasma and tissue bioanalysis. Turn-around times are industry-leading. You can expect results within 48 hours of sample submission.
Extensive experience with mcirosampling to support PK and PK/PD and pre-clinical biomarker measurements. Microvolumes of whole blood onto solid support (e.g., MITRA) or into serum collection tubes (e.g., Sarstedt). Following sample preparation, microsamples are analyzed by LC/MS/MS and drug levels quantified with confidence.
Clinical Assay Development
Method development and pre-validation of laboratory developed tests applying state-of-art LC/MS/MS
drugs of abuse
THC and related species